![]() These include dermal skin substitute and allogenic bilayered human skin. 21.10.1.6 Bioengineered cell-based therapies Studies so far show that no one single biological dressing is clearly superior among all the biological dressings. This increase in available dressings for use in the diabetic foot is positive however, there is no evidence yet to guide us as to which dressing is best to use. These effects can prevent degradation of the matrix that is present and simultaneously increase collagen and granulation tissue formation. These agents can help reduce inflammatory cytokines and proteases while increasing growth factors. They can comprise collagen, extracellular matrix proteins, chitosan, fibrin, hyaluronic acid, and elastin. They can release therapeutic agents such as growth factors, peptides, and stem cells. These are aimed at rebuilding the extracellular matrix. These help to maintain a moist environment and are ideal for use on chronic wounds. These include hydrogels, alginates, hydrocolloids, silver, and biological dressings. This has been shown to be an effective aid in the debridement and promotion of wound healing that can be applied to the diabetic. It uses a high-pressure jet stream of normal saline to do this and has proven to be a very quick and effective method of debridement. This is a new effective tool that cuts and debrides tissue in a thin layer while simultaneously aspirating it away. 21.10.1.2 The Versajet hydrosurgery system (Smith & Nephew) They can therefore be an effective adjunct to surgical debridement. The larvae debride dead tissue and their secretions target both Gram-negative and Gram-positive bacteria. Larval therapy to debride and disinfect has been used for chronic wounds which are difficult to heal. The new debridement methods and wound healing strategies are evolving although the use of scalpel and scissors for debridement remains the benchmark in the management of diabetic foot ulcers.
0 Comments
Leave a Reply. |